Nano-HAp safety
FLUIDINOVA’s nanoXIM•CarePaste is currently the only nano-hydroxyapatite in the world scrutinized and approved as safe for oral care cosmetics by the Scientific Committee on Consumer Safety (SCCS) European authorities.
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Dental hypersensitivity, a short and sharp pain, prevents us from drinking hot coffee, ice cream, or even an orange juice without feeling pain. Certain foods and drinks (hot, cold, acidic, etc.) are considered aggressions to our teeth, resulting in the exposure of dentin tubules and the underlying nerves to the external environment, causing our dentin to lose its protective covering.
Nano-HAp has great potential in the treatment of dental hypersensitivity, as its nanosized particles can be incorporated inside the dentin tubules. Consequently, they seal, reducing overall pain.
HAp has great potential in the treatment of dental hypersensitivity, as it can be incorporated inside the dentin tubules. Consequently, they seal, reducing overall pain.
As a result, a new layer is formed, remineralizing the tooth enamel and protecting the tooth surface. This prevents the appearance of new cavities and makes teeth resistant to acid attacks from our favorite meals.
As a result, a new layer is formed, remineralizing the tooth enamel and protecting the tooth surface. This prevents the appearance of new cavities and makes teeth resistant to acid attacks from our favorite meals.
The deposition of HAp on the enamel surface improves its smoothness for better light reflection, and consequently brighter and whiter teeth.
The deposition of nano-HAp on the enamel surface improves its smoothness for better light reflection, and consequently brighter and whiter teeth.
Hydroxyapatite’s adhesion to enamel and dentin tubule occlusion depends greatly on its particle size, with nanoparticles and small microparticles being much more effective than conventional micron-sized particles.
In the following diagram, we can see the difference in particle size between nanoXIM nano-HAp, nanoXIM micro-HAp and conventional micro-HAp, bearing in mind that dentin tubules have an average diameter of 2.5 μm.
When it comes to dentin tubule occlusion, conventional micro-HAp is too large to be effective at sealing dentin tubules. On the other hand, nanoXIM nano-HAp, which is 50x smaller than the average diameter of dentin tubules, and nanoXIM micro-HAp (1.1 μm), which is also smaller than dentin tubules, are both able to effectively occlude the dentin tubules, strongly reducing dental hypersensitivity.
Fabritius-Vilpoux et al. (2019) found that effective adhesion to enamel only occurs with particles up to 1.3 μm in diameter. Because conventional micro-HAp size is excessively large, above 5 μm, it results in poor or nonexistent adhesion to the enamel. On the other hand, nanoXIM nano-HAp size is 25x smaller than the upper limit of 1.3 μm determined by Fabritius-Vilpoux et al., and nanoXIM micro-HAp size is about 1.1 μm, which is also below the 1.3 μm mentioned. As a result, both nanoXIM nano-HAp and micro-HAp are capable of adhering effectively to the enamel surface, remineralizing it and protecting the tooth surface, thereby preventing the appearance of new cavities.
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FLUIDINOVA’s nanoXIM•CarePaste is currently the only nano-hydroxyapatite in the world scrutinized and approved as safe for oral care cosmetics by the Scientific Committee on Consumer Safety (SCCS) European authorities.
